URI researchers discover way to boost immunotherapy effectiveness to fight cancer

RESEARCHERS AT THE University of Rhode Island and Yale University have discovered a new method to boost the effectiveness of immunotherapy against cancer by using a delivery agent targeting the acidity in tumors. The image shows an untreated tumor, top left, which is highly acidic, as indicated by its response to fluorescent dye, top right. It shows the tumor days after treatment, bottom left, where the tumor stroma is disrupted and pH decreases, bottom right. / COURTESY UNIVERSITY OF RHODE ISLAND
SOUTH KINGSTOWN – Researchers from the University of Rhode Island and Yale University have demonstrated a new approach to fight cancer by using a molecular delivery system that targets acidity to deliver immunotherapy drugs. The results, published in Frontiers of Oncology, show that a single dose of the immunotherapy drug was able to eradicate even…

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